False memories prime immune system for future attacks

IN A police line-up, a falsely remembered face is a big problem. But for the body's police force – the immune system – false memories could be a crucial weapon.

When a new bacterium or virus invades the body, the immune system mounts an attack by sending in white blood cells called T-cells that are tailored to the molecular structure of that invader. Defeating the infection can take several weeks. However, once victorious, some T-cells stick around, turning into memory cells that remember the invader, reducing the time taken to kill it the next time it turns up.

Conventional thinking has it that memory cells for a particular microbe only form in response to an infection. "The dogma is that you need to be exposed," says Mark Davis of Stanford University in California, but now he and his colleagues have shown that this is not always the case.

The team took 26 samples from the Stanford Blood Center. All 26 people had been screened for diseases and had never been infected with HIV, herpes simplex virus or cytomegalovirus. Despite this, Davis's team found that all the samples contained T-cells tailored to these viruses, and an average of 50 per cent of these cells were memory cells.

The idea that T-cells don't need to be exposed to the pathogen "is paradigm shifting," says Philip Ashton-Rickardt of Imperial College London, who was not involved in the study. "Not only do they have capacity to remember, they seem to have seen a virus when they haven't."

So how are these false memories created? To a T-cell, each virus is "just a collection of peptides", says Davis. And so different microbes could have structures that are similar enough to confuse the T-cells.

To test this idea, the researchers vaccinated two people with an H1N1 strain of influenza and found that this also stimulated the T-cells to react to two bacteria with a similar peptide structure. Exposing the samples from the blood bank to peptide sequences from certain gut and soil bacteria and a species of ocean algae resulted in an immune response to HIV (Immunology, doi.org/kgg).

The finding could explain why vaccinating children against measles seems to improve mortality rates from other diseases. It also raises the possibility of creating a database of cross-reactive microbes to find new vaccination strategies. "We need to start exploring case by case," says Davis.

"You could find innocuous pathogens that are good at vaccinating against nasty ones," says Ashton-Rickardt. The idea of cross-reactivity is as old as immunology, he says. But he is excited about the potential for finding unexpected correlations. "Who could have predicted that HIV was related to an ocean algae?" he says. "No one's going to make that up!"

This article appeared in print under the headline "False memories prime our defences"

If you would like to reuse any content from New Scientist, either in print or online, please contact the syndication department first for permission. New Scientist does not own rights to photos, but there are a variety of licensing options available for use of articles and graphics we own the copyright to.

All comments should respect the New Scientist House Rules. If you think a particular comment breaks these rules then please use the "Report" link in that comment to report it to us.

If you are having a technical problem posting a comment, please contact technical support.

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Australia seeks answers from Israel on 'Prisoner X'

SYDNEY: Canberra said Sunday it was seeking answers from Israel over the death in 2010 of an Australian known as "Prisoner X" in a Tel Aviv jail as part of its own probe into the case.

Foreign Minister Bob Carr said his office was preparing a formal report into the circumstances surrounding the death of the prisoner, identified in Australian media as Ben Zygier, 34, who Israel says committed suicide.

That the detainee, held in a high security prison under continuous surveillance, managed to hang himself has raised questions and fed conspiracy theories that have been reported by the Israeli and Australian media.

Many questions remain unanswered in the mysterious case, with a senior unnamed Israeli official telling The Australian newspaper that Australian officials had interrogated the prisoner on suspicion of spying for Mossad.

Carr said foreign office chief Peter Varghese was preparing a report which would "canvass all the consular contact between Australia and between Israel" including contact between security agencies.

"We have asked the Israeli government for a contribution to that report," Carr told reporters in Sydney.

"We want to give them an opportunity to submit to us an explanation of how this tragic death came about."

If the report showed "any areas where we can improve our contact in consular cases like this", Carr said, "it will have practical effect when there are cases in the future where an Australian citizen is treated in a comparable way."

"I need to know what the contact was between Australian agencies and those of Israel, and I need to see what the Israelis want to tell Australia," he said. "The key is to get all the information."

Carr, foreign minister since early 2012, originally said the Australian government had not been informed of the prisoner's plight.

He later backtracked on this claim, conceding that Canberra was told in February 2010 -- 10 months before the death -- that Israel had detained an Australian-Israeli citizen on national security grounds.

Carr's predecessor Kevin Rudd, foreign minister at the time of the prisoner's death, said Sunday it was important that Australia "get to the bottom of this".

"(I was) deeply surprised to hear not only had this person been incarcerated, but subsequently died in custody," Rudd told Sky News.

"The tradition of this government has to be robust on these matters, even with a country with whom we've had the friendliest of relationships."

- AFP/ir

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Russian meteorite: The conspiracy theories

A strange time for a military attack?

(Credit:
CNN; screenshot by Chris Matyszczyk/CNET)

A good hearty conspiracy theory can shine a sharp light on two of humanity's most enduring traits.

One, of course, is humanity's boundless imagination. The other is humanity's essential suspicion of humanity.

So while you might be deeply immersed in Bill Nye's explanation of the Russian meteorite, those with darker sensibilities have filled the Web with their fears and hauntings about the phenomenon.

There are few nations with greater awareness of dark sensibilities than Russia. The fact that there seems to be little evidence of meteorite fragments on the ground has encouraged some Russians to offer their own suspicions.

As the Toronto Globe and Mail reports, nationalist leader Vladimir Zhirinovsky hasn't been slow to offer something of a Hot War perspective.

"It's not meteors falling. It's a new weapon being tested by the Americans," he was quoted as saying.

We know from our recent experience of North Korea that weapons testing is an imprecise science.

But if you were an American in the mood to test a weapon, would Chelyabinsk, Russia, be your very first choice of place for the experiment?

Perhaps Tallahassee; Area 51; and Bialystok, Poland, were all unavailable due to prior commitments. Or perhaps it wasn't the Americans, but, say, the North Koreans, who mistook Chelyabinsk for, say, Chelsea.

Zhirinovsky's rather emotionally manipulative offering was countered by Russia's Emergency Ministry, which dedicated itself to an extensive rebuttal of his belief (and that of others) that this was some sort of military thing. The rebuttal? "Rubbish."

But that wasn't going to put off the local media, was it? Not only do they have papers to sell, they also have theories to expound to a troubled nation and world.

So, as The Atlantic reports, the local Znak newspaper accepted that this was a meteorite but insisted the explosion was caused by military defense blowing it up.

More Technically Incorrect

Yes, of course it has a source in the military. You thought it didn't?

Though I've watched a few movies in which exciting things happen, I don't find it easy to imagine that some sort of terrestrially created missile-laden aircraft could really explode a meteorite in such a manner.

It is easier to imagine, though, that politicians like Zhirinovsky might take the opportunity to foment a little rage.

Indeed, Alex Jones' infamously well-guarded Infowars site offered that Zhirinovsky insisted that America -- in the person of Secretary of State John Kerry -- had tried to give Russia advance notice of its "attack."

The Drudge Report led me to a piece at Foreign Policy that explained that Sergey Lavrov, Russia's foreign minister, simply hadn't called Kerry back.

Which all suggests that Russia isn't, after all, living in fear of an attack from the U.S. Especially one over Chelyabinsk.

On balance, I prefer to currently believe Nye. He is the science guy, after all. And science guys know scientific events when they see them.

I hope.

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Picture Archive: Making Mount Rushmore, 1935-1941

Photograph from Rapid City Chamber of Commerce/National Geographic

There's no such thing as Presidents' Day.

According to United States federal government code, the holiday is named Washington's Birthday, and has been since it went nationwide in 1885.

But common practice is more inclusive. The holiday expanded to add in other U.S. presidents in the 1960s, and the moniker Presidents' Day became popular in the 1980s and stuck. It may be that George Washington (b. February 22, 1732) andAbraham Lincoln (b. February 12, 1809) still get the lion's share of attention—and appear in all the retail sale ads—on the third Monday in February, but the popular idea is that all 44 presidents get feted.

Mount Rushmore is a lot like that one day a year writ large—and in granite. It's carved 60 feet (18 meters) tall and 185 feet (56 meters) wide, from Washington's right ear to Lincoln's left.

The monument's sculptor, Gutzon Borglum, grew up in Idaho, a first-generation American born to Danish parents. He studied art in France and became good friends with Auguste Rodin. Borglum mostly worked in bronze, but in the early 1910s he was hired to carve the likenesses of Confederate leaders into Stone Mountain in Georgia.

He was about to be fired from that job for creative differences about the same time that a South Dakota historian named Doane Robinson had an idea. Robinson wanted to have a monument carved into the Black Hills of South Dakota, maybe Western historical figures like Chief Red Cloud and Lewis and Clark, each on their own granite spire. (Plan a road trip in the Black Hills.)

Robinson hired Borglum and gave him carte blanche. Borglum was looking for something with national appeal, so he chose to depict four presidents: George Washington, Thomas Jefferson, Theodore Roosevelt, and Abraham Lincoln.

Borglum wanted to represent the first 150 years of the nation's history, choosing four presidents as symbols of their respective time periods. He took a tour of western South Dakota, searching for an ideal canvas.

The sculptor was looking for three things: a surface strong enough to sculpt, a mountain big enough to hold several figures, and a mountain face that received morning sunlight. Mount Rushmore fit the bill and was already part of a national forest, so it was easy to set aside as a national memorial.

Work started in 1927. Calvin Coolidge attended the dedication ceremony. It took 14 years to finish the carving, conducted mostly in summertime because of the area's harsh winters.

There were approximately 30 workers on the mountain at any give time. In total about 400 had worked on it by the time the monument was finished. Though the project involved thousands of pounds of dynamite and perilous climbs, not a single person died during the work.

Borglum himself died of natural causes in 1941, though, just six months before the project was declared "closed as is" by Congress that Halloween. His son Lincoln—named for his father's favorite president—took over.

In the photo above, a worker refines the details of Washington's left nostril.

About 90 percent of the mountain was carved using dynamite, which could get within 3 to 5 inches (8 to 13 centimeters) of the final facial features. For those last few inches, workers used what was known as the honeycomb method: Jackhammer workers pounded a series of three-inch-deep holes followed up by chiselers who knocked off the honeycomb pieces to get the final shape. Then carvers smoothed the "skin's" surface.

—Johnna Rizzo

February 16, 2013

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Meteor Blast Creates Rush to Cash In

The shattered glass and broken walls caused by the massive explosion of a monstrous meteor over this remote, industrial Russian city is not even cleaned up, and people are already trying to cash in.

Some residents want to turn this city known mostly for its tank factory into a tourist destination, while others from all around the world are determined to find fragments of the meteorite.

Meteor hunters say it's a once in a lifetime opportunity. A small piece of the space rock that exploded over Russia Friday could be worth thousands of dollars, and bigger chunks could fetch hundreds of thousands.

SEE PHOTOS: Meteorite Crashes in Russia

"I haven't been able to sleep for the last two days because of this," said Michael Farmer, who runs the website Meteor Hunter. "This is a once in a lifetime event. We've never seen anything like this in the last hundred years."

He said he started planning a trip to Chelyabinsk as soon as the meteorite exploded.

"The next morning I was on the phone working on visas. I'd like to get a visa and get over to Russia as quickly as possible," he said. "When this type of thing happens, you know hours count so we try to arrange that as fast as possible."

A day after a massive meteor exploded over this city in central Russia, a monumental cleanup effort is under way.

Authorities have deployed around 24,000 troops and emergencies responders to help in the effort.

Officials say more than a million square feet of windows -- the size of about 20 football fields -- were shattered by the shockwave from the meteor's blast. Around 4,000 buildings in the area were damaged.

Nasha gazeta, www.ng.kz/AP Photo

The injury toll climbed steadily on Friday. Authorities said today it now stands at more than 1,200. Most of those injuries were from broken glass, and only a few hundred required hospitalization.

According to NASA, this was the biggest meteor to hit Earth in more than a century. Preliminary figures suggest it was 50 feet wide and weighed more than the Eiffel Tower.

NASA scientists have also estimated the force of the blast that occurred when the meteor fractured upon entering Earth's atmosphere was approximately 470 kilotons -- the equivalent of about 30 Hiroshima bombs, but it did not cause major damage because it occurred so high in the atmosphere.

"This was caused by a small asteroid, about 15 meters in diameter, coming in at around 18 kilometers per second, that's in excess of 40-thousand miles per hour," NASA planetary scientist Paul Abell said. "As the asteroid comes in, it interacts with the atmosphere and effectively it converts all the energy, the kinetic energy of the asteroid, the mass of the asteroid and the velocity and it's actually that velocity, the asteroid just effectively explodes and that creates the pressure wave, the blast wave that comes down."

Treasure hunters hoping to cash in on the bits of space rock aren't the only ones eager to find pieces of the meteor, Abell said. Scientists say the material could offer valuable information.

"One of the things we'd like to learn is first of all, what was the composition of the asteroid, where did it come from," he said. "We know it came from the asteroid belt but can we link it to a bigger asteroid and also, get an idea of the dispersal pattern."

Residents said they still can't believe it happened here.

"It was something we only saw in the movies," one university student said. "We never thought we would see it ourselves."

Throughout the city, the streets are littered with broken glass. Local officials have announced an ambitious pledge to replace all the broken windows within a week. In the early morning hours, however, workers could still be heard drilling new windows into place.

Authorities have sent divers into a frozen lake outside the city, where a large chunk of the meteor is believed to have landed, creating a large hole in the ice. By the end of the day they had not found anything.

Read More..

False memories prime immune system for future attacks

IN A police line-up, a falsely remembered face is a big problem. But for the body's police force – the immune system – false memories could be a crucial weapon.

When a new bacterium or virus invades the body, the immune system mounts an attack by sending in white blood cells called T-cells that are tailored to the molecular structure of that invader. Defeating the infection can take several weeks. However, once victorious, some T-cells stick around, turning into memory cells that remember the invader, reducing the time taken to kill it the next time it turns up.

Conventional thinking has it that memory cells for a particular microbe only form in response to an infection. "The dogma is that you need to be exposed," says Mark Davis of Stanford University in California, but now he and his colleagues have shown that this is not always the case.

The team took 26 samples from the Stanford Blood Center. All 26 people had been screened for diseases and had never been infected with HIV, herpes simplex virus or cytomegalovirus. Despite this, Davis's team found that all the samples contained T-cells tailored to these viruses, and an average of 50 per cent of these cells were memory cells.

The idea that T-cells don't need to be exposed to the pathogen "is paradigm shifting," says Philip Ashton-Rickardt of Imperial College London, who was not involved in the study. "Not only do they have capacity to remember, they seem to have seen a virus when they haven't."

So how are these false memories created? To a T-cell, each virus is "just a collection of peptides", says Davis. And so different microbes could have structures that are similar enough to confuse the T-cells.

To test this idea, the researchers vaccinated two people with an H1N1 strain of influenza and found that this also stimulated the T-cells to react to two bacteria with a similar peptide structure. Exposing the samples from the blood bank to peptide sequences from certain gut and soil bacteria and a species of ocean algae resulted in an immune response to HIV (Immunology, doi.org/kgg).

The finding could explain why vaccinating children against measles seems to improve mortality rates from other diseases. It also raises the possibility of creating a database of cross-reactive microbes to find new vaccination strategies. "We need to start exploring case by case," says Davis.

"You could find innocuous pathogens that are good at vaccinating against nasty ones," says Ashton-Rickardt. The idea of cross-reactivity is as old as immunology, he says. But he is excited about the potential for finding unexpected correlations. "Who could have predicted that HIV was related to an ocean algae?" he says. "No one's going to make that up!"

This article appeared in print under the headline "False memories prime our defences"

If you would like to reuse any content from New Scientist, either in print or online, please contact the syndication department first for permission. New Scientist does not own rights to photos, but there are a variety of licensing options available for use of articles and graphics we own the copyright to.

All comments should respect the New Scientist House Rules. If you think a particular comment breaks these rules then please use the "Report" link in that comment to report it to us.

If you are having a technical problem posting a comment, please contact technical support.

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Malaysia detains Australian lawmaker at airport

KUALA LUMPUR: Malaysia detained an Australian lawmaker at Kuala Lumpur airport Saturday and is expected to deport him, an activist said, in a move Canberra described as "disappointing and surprising".

Nick Xenophon, an outspoken independent Senator, was detained at the international airport near the capital Kuala Lumpur upon his arrival from Melbourne.

"He informed me that he is being deported," Ambiga Sreenevasan, a lawyer and co-chair of electoral reform group Bersih, told AFP after she spoke to Xenophon early Saturday.

The Malaysian government is yet to comment on the circumstances surrounding Xenophon's detention but Ambiga said it appeared to be "under the Security Offences Act".

"(Authorities) said he is a security risk," she added.

Xenophon, who has travelled to Malaysia several times, was to meet Bersih members and others including opposition leader Anwar Ibrahim and Election Commission officials next week, Ambiga said.

Australia's Foreign Minister Bob Carr said Australian officials were in touch with Xenophon, as well as Malaysia's foreign and home ministers, and were seeking his "swift release" from custody.

"Senator Xenophon's detention is a surprising and disappointing act from a country with which Australia routinely maintains strong diplomatic relations," he said in a statement.

The Security Offences (Special Measures) Act, or SOSMA, was introduced in Malaysia last year to replace the much-criticised colonial-era Internal Security Act, which allowed indefinite detention without trial.

Prime Minister Najib Razak has touted SOSMA and other reforms to show he is granting more civil liberties, but rights group have criticised the new act, saying it still gives broad powers to detain people for too long.

Malaysia has deported several foreigners in recent years. Among them was a French lawyer representing a human rights group in an inquiry into alleged corruption linked to Najib.

- AFP/ck

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E-orders for 128GB Surface Pro to ship in 2-3 weeks -- Microsoft

Microsoft provided another update at the end of this week regarding the availability of its sold-out 128GB version of the Surface Pro.

A February 15 Surface Blog post said that those ordering through the Microsoft online store in the U.S. can place an order for the 128GB model and have it ship in two to three weeks.

The new post also provided updated information for those wanting to "reserve" the Intel-based PC/tablet hybrid
Surface Pro devices. Up until now, Microsoft officials have declined comment when asked whether users would be able to pre-order Surface Pros.

Here's the latest Surface Pro availability guidance:

At Best Buy (U.S.): Inventory levels are increasing and many Best Buy stores have Surface Pro units for sale in-store. If the store does not have stock, you can reserve a Surface Pro (64GB and 128GB). Please note that Best Buy is only taking reservations in their stores for Surface Pro based on new inventory they know is coming in next week, so it's possible that reservations could become "sold out."

At Staples (U.S.): Many Staples stores have Surface Pro units for sale in stores. If the store does not have stock, you can place a kiosk order in store to purchase Surface Pro 64GB for delivery.

For Canada: In Best Buy and Future Shop stores you can reserve the 64GB Surface Pro in stores at this time. Staples has availability online while inventory lasts and more inventory has been ordered to ensure store availability in the near future. More details to come on the 128GB Surface Pro availability in Canada.

It seems that Staples is making the 128GB Surface Pros available for order online and that they are not being stocked in Staples brick-and-mortar outlets, as I noted earlier this week.

Microsoft is "work(ing) around the clock to meet that demand with production and get new inventory into retail," the post concluded. Company officials advise customers interested in the Pros to call ahead before venturing to stores this weekend, in spite of guidance earlier in the week that more stores would have stock on hand starting on Saturday, February 16.

It's still unclear why there are not enough Surface Pros on the market. Is it that Microsoft seriously underestimated demand for 128GB Surface Pros -- a happy problem for the Softies? Or have supply-chain problems led to device shortages (a not-so-happy problem)? Microsoft's Surface Pro devices went on sale February 9.

This story originally appeared on ZDNet under the headline "Microsoft: Online orders for 128 GB Surface Pro to ship in two to three weeks."

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Severe Weather More Likely Thanks to Climate Change

Jane J. Lee

BOSTON—Wildfires. Droughts. Super storms.

As opposed to representing the unfortunate severe weather headlines of the last year, scientists said Friday that climate change has increased the likelihood of such events moving forward.

And though the misery is shared from one U.S. coast to another, scientists speaking at the annual American Association for the Advancement of Science meeting in Boston said, the type of extreme event may vary significantly from region to region. (Related: "6 Ways Climate Change Will Affect You.")

Heat waves have become more frequent across the United States, with western regions setting records for the number of such events in the 2000s, said Donald Wuebbles, a geoscientist with the University of Illinois at Urbana-Champaign.

But the Midwest and Northeast have experienced a 45 percent and 74 percent increase, respectively, in the heaviest rainfalls those regions have seen since 1950.

The extreme drought that plagued Texas in 2011 has spread to New Mexico, Louisiana, Oklahoma, and northern Mexico, said John Nielsen-Gammon, Texas State's climatologist at Texas A&M University in College Station.

"The science is clear and convincing that climate change is happening and it's happening rapidly. There's no debate within the science community ... about the changes occurring in the Earth's climate and the fact that these changes are occurring in response to human activities," said Wuebbles.

In 2011 and 2012, major droughts, heat waves, severe storms, tornadoes, floods, hurricanes, and wildfires caused about $60 billion in damages each year, for a total of about $120 billion.

According to the National Oceanic and Atmospheric Administration Climactic Data Center, these were some of the costliest weather events in the country's history, said Wuebbles.

President Obama argued in his State of the Union address this week that the time is ripe to address climate change, saying he would skirt Congress to make such changes, if necessary.

His proposals included a system similar to the cap-and-trade proposal killed in Congress during his first term, new regulations for coal-burning power plants, and a promise to promote energy efficiency and R&D efforts into cleaner technologies. (Related: "Obama Pledges U.S. Action on Climate, With or Without Congress.")

The researchers said they are glad to see that addressing climate change is on the President's agenda. But they stressed that they wanted the public to have access to accurate, scientifically sound information, not just simplified talking points.

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Carnival Cruise Ship Hit With First Lawsuit

The first lawsuit against Carnival Cruise Lines has been filed and it is expected to be the beginning of a wave of lawsuits against the ship's owners.

Cassie Terry, 25, of Brazoria County, Texas, filed a lawsuit today in Miami federal court, calling the disabled Triumph cruise ship "a floating hell."

"Plaintiff was forced to endure unbearable and horrendous odors on the filthy and disabled vessel, and wade through human feces in order to reach food lines where the wait was counted in hours, only to receive rations of spoiled food," according to the lawsuit, obtained by ABCNews.com. "Plaintiff was forced to subsist for days in a floating toilet, a floating Petri dish, a floating hell."

Click Here for Photos of the Stranded Ship at Sea

The filing also said that during the "horrifying and excruciating tow back to the United States," the ship tilted several times "causing human waste to spill out of non-functioning toilets, flood across the vessel's floors and halls, and drip down the vessel's walls."

Terry's attorney Brent Allison told ABCNews.com that Terry knew she wanted to sue before she even got off the boat. When she was able to reach her husband, she told her husband and he contacted the attorneys.

Allison said Terry is thankful to be home with her husband, but is not feeling well and is going to a doctor.

Carnival's Triumph Passengers: 'We Were Homeless' Watch Video

Girl Disembarks Cruise Ship, Kisses the Ground Watch Video

Carnival Cruise Ship Passengers Line Up for Food Watch Video

"She's nauseated and actually has a fever," Allison said.

Terry is suing for breach of maritime contract, negligence, negligent misrepresentation and fraud as a result of the "unseaworthy, unsafe, unsanitary, and generally despicable conditions" on the crippled cruise ship.

"Plaintiff feared for her life and safety, under constant threat of contracting serious illness by the raw sewage filling the vessel, and suffering actual or some bodily injury," the lawsuit says.

Despite having their feet back on solid ground and making their way home, many passengers from the cruise ship are still fuming over their five days of squalor on the stricken ship and the cruise ship company is likely to be hit with a wave of lawsuits.

"I think people are going to file suits and rightly so," maritime trial attorney John Hickey told ABCNews.com. "I think, frankly, that the conduct of Carnival has been outrageous from the get-go."

Hickey, a Miami-based attorney, said his firm has already received "quite a few" inquiries from passengers who just got off the ship early this morning.

"What you have here is a) negligence on the part of Carnival and b) you have them, the passengers, being exposed to the risk of actual physical injury," Hickey said.

The attorney said that whether passengers can recover monetary compensation will depend on maritime law and the 15-pages of legal "gobbledygook," as Hickey described it, that passengers signed before boarding, but "nobody really agrees to."

One of the ticket conditions is that class action lawsuits are not allowed, but Hickey said there is a possibility that could be voided when all the conditions of the situation are taken into account.

One of the passengers already thinking about legal action is Tammy Hilley, a mother of two, who was on a girl's getaway with her two friends when a fire in the ship's engine room disabled the vessel's propulsion system and knocked out most of its power.

"I think that's a direction that our families will talk about, consider and see what's right for us," Hilley told "Good Morning America" when asked if she would be seeking legal action.

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Sand-grain-sized drum extends reach of quantum theory

The banging of a tiny drum heralds the intrusion of the weird world of quantum mechanics into our everyday experience. Though no bigger than a grain of sand, the drum is the largest object ever to have been caught obeying the uncertainty principle, a central idea in quantum theory.

As well as extending the observed reach of quantum theory, the finding could complicate the hunt for elusive gravitational waves : it suggests that the infinitesimal motion caused by these still-hypothetical ripples in spacetime could be overwhelmed by quantum effects.

The uncertainty principle says that you cannot simultaneously determine both a particle's exact position and momentum. For example, bouncing a photon off an electron will tell you where it is, but it will also change the electron's motion, creating fresh uncertainty in its speed.

This idea limits our ability to measure the properties of very small objects, such as electrons and atoms. The principle should also apply to everyday, macroscopic objects, but this has not been tested – for larger objects, the principle's effects tend to be swamped by other uncertainties in measurement, due to random noise, say.

Quantum drum

To extend the known reach of the uncertainty principle, Tom Purdy and colleagues of the University of Colorado, Boulder, created a drum by tightly stretching a 40-nanometre-thick sheet of silicon nitride over a square frame with sides of half a millimetre – about the width of a grain of sand. They placed the drum inside a vacuum chamber cooled to a few degrees above absolute zero, minimising any interference by random noise.

By continuously firing a stream of photons at the drum they were able to get increasingly precise measurements of the position of the skin at any moment. However, this also caused the skin to vibrate at an unknown speed. When they attempted to determine its momentum, the error in their measurement had increased – just as the uncertainty principle predicts.

"You don't usually have to think about quantum mechanics for objects you can hold in your hand," says Purdy.

That the uncertainty principle holds sway at such a large scale could affect the hunt for gravitational waves, which are predicted by Einstein's theory of general relativity but have never been detected.

Mitigation strategy

Gravitational wave detectors look for very slight changes in the distance between two test masses caused by passing spacetime ripples. Purdy says his team's experiment confirms long-held suspicions that quantum uncertainty could overwhelm these very small changes.

Now he and others can use the drum to explore more advanced measurement techniques to mitigate the effects. For example, uncertainty in an object's momentum could lead to future uncertainty in its position and there should be ways to minimise such knock-on effects. "You can't avoid the uncertainty principle, but you can in some clever ways make it [such that] increasing the momentum doesn't add back to the uncertainty in position at a later time," says Purdy.

His experiment is a neat demonstration of the breakdown of the traditional notion that the atomic world is quantum while the macroscopic world is classic, says Gerard Milburn of the University of Queensland in Brisbane, Australia, who was not involved in the work. Previous, attempts to blur the quantum-classical divide have involved entangling diamonds and demonstrating quantum superposition in a strip of metal.

Despite these feats, Milburn doesn't rule out the prospect of a breakdown on really large scales. "Of course maybe one day we will see quantum mechanics fail at some scale. Testing it to destruction is a good motivation for going down this path," he says.

Journal reference: Science, DOI: 10.1126/science.1231282

If you would like to reuse any content from New Scientist, either in print or online, please contact the syndication department first for permission. New Scientist does not own rights to photos, but there are a variety of licensing options available for use of articles and graphics we own the copyright to.

All comments should respect the New Scientist House Rules. If you think a particular comment breaks these rules then please use the "Report" link in that comment to report it to us.

If you are having a technical problem posting a comment, please contact technical support.

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MediaCorp celebrates 50 years of television

SINGAPORE: Singapore's leading media company MediaCorp is celebrating 50 years of broadcasting with year-long celebrations.

Highlights include special programmes on each channel that allow audiences to enjoy a new experience while viewing television content, via multi-platform, second screen and on-ground vehicles.

There will also be roadshows in May and a charity special in September.

The year-long jubilee will culminate in a grand variety countdown special on New Year's Eve.

CEO of MediaCorp Shaun Seow said: "Singapore television has come a long way from its pilot service 50 years ago. It transited to colour in the 1970s, and to the digital form we know it today - consumed as much on the TV set in the living room as on the go.

"Its content has also evolved, reflecting the mores of the times and telling the story of our nation building.

"As we celebrate this milestone anniversary, we want to thank all our viewers who've grown up with us, cried with us, laughed with us. We're also reaching out to a new generation of viewers who want to be engaged via social media.

"Whatever the form, we will strive to innovate and improve ourselves so that MediaCorp continues to be an integral part of the lives of Singaporeans."

- CNA/ck

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Staples will reportedly begin selling Apple products in U.S.

Might Staples customers soon be able to get their hands on Apple's 4th-generation iPad at the office supply store?

(Credit:
Apple)

Apple products will soon be showing up at Staples stores, according to tweets from employees at the office supply store chain.

Regis Mulot, the vice president of international human resources at Staples, made the announcement this afternoon:

In addition to Mulot's tweet, Erin LaFlamme, a Strategic Accounts coordinator at Staples, tweeted her joy at the deal (and the apparent gift of Apple pie):

Mike Goggin, a field services manager at Staples, tweeted that it was a done deal:

Rumors of just such a tie-up have been circulating for a couple of months. Initially offering its products only at CompUSA, the company has gradually expanded its retail channels to include Walmart, Best Buy, Target, and RadioShack.

The move would be a big win for both companies. It would give Apple exposure at one of the largest office supply chains in the U.S., while expanding Staples' customer base with Apple's loyal customers.

It was not clear which products would be offered or when they might arrive in stores. CNET has contacted Staples and Apple for comment and will update this report when we learn more.

(Via AppleInsider)

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Why We Walk … and Run … And Walk Again to Get Where We're Going

You have to get to a bus stop to catch the once-an-hour express ... or to a restaurant to meet a friend ... or to a doctor's office. You've got maybe a half a mile to cover and you're worried you'll be late. You run, then you stop and walk, then run some more.

But wait. Wouldn't it be better to run the whole way?

Not necessarily.

A new study by an assistant professor of mechanical engineering at Ohio State University tests the theory that people subconsciously mix walking and running so they get where they need to. The idea is that "people move in a manner that minimizes energy consumption," said the professor, Manoj Srinivasan.

Srinivasan asked 36 subjects to cover 400 feet (122 meters), a bit more than the length of a football field. He gave them a time to arrive at the finish line and a stopwatch. If the deadline was supertight, they ran. If they had two minutes, they walked. And if the deadline was neither too short nor too far off, they toggled between walking and running.

The takeaway: Humans successfully make the walk-run adjustment as they go along, based on their sense of how far they have to go. "It's not like they decide beforehand," Srinivasan said. (Get tips, gear recommendations, and more in our Running Guide.)

The Best Technique for "the Twilight Zone"

"The mixture of walking and running is good when you have an intermediate amount of time," he explained. "I like to call it 'the Twilight Zone,' where you have neither infinite time nor do you have to be there now."

That ability to shift modes served ancient humans well. "It's basically an evolutionary argument," Srinivasan said. A prehistoric human seeking food would want to move in a way that conserves some energy so that if food is hard to find, the hunter won't run out of gas—and will still be able to rev it up to escape predators.

The study, published on January 30 in the Journal of the Royal Society Interface, doesn't answer that question of how we make such adjustments.

Runners: Take a Break if You Need It

The mix of walking and running is also something that nonelite marathoners are familiar with. Covering 26.2 miles might take less of a toll if the runner stops running from time to time, walks a bit, then resumes a jogging pace. "You use less energy overall and also give yourself a bit of a break," Srinivasan noted. (Watch: An elite marathoner on her passion for running.)

One take-home lesson is: Runners, don't push it all the time. A walk-run mix will minimize the energy you expend.

Lesson two: If you're a parent walking with your kid, and the kid lags behind, then runs to catch up, then lags again, the child isn't necessarily trying to annoy you. Rather, the child is perhaps exhibiting an innate ability to do the walk-run transition.

Potential lesson three: The knowledge that humans naturally move in a manner that minimizes energy consumption might be helpful in designing artificial limbs that feel more natural and will help the user reduce energy consumption.

The big question for Manoj Srinivasan: Now that he has his walk-run theory, does he consciously switch between running and walking when he's trying to get somewhere? "I must admit, no," he said. "When I want to get somewhere, I just let the body do its thing." But if he's in a rush, he'll make a mad dash.

"Talk to you tomorrow," he signed off in an email to National Geographic News. "Running to get to teaching now!"

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Passengers Start to Get Off Disabled Cruise Ship

The ordeal of the disabled Carnival Triumph cruise ship carrying 4,000 passengers and crew appeared to be almost over, with people starting to disembark in Mobile, Ala., after days at sea without power in often squalid conditions.

After the ship arrived at port around 9:30 p.m. local time (10:30 p.m. ET), Carnival president and CEO Gerry Cahill praised the ship's crew and told reporters that he was headed on board to apologize directly to its passengers.

Passengers appeared to begin disembarking around 10:15 p.m. CT (11:15 p.m. ET).

The Carnival Triumph departed Galveston, Texas, Thursday and lost power Sunday after a fire in the engine room disabled the vessel's propulsion system and knocked out most of its power.

After power went out, passengers texted ABC News that sewage was seeping down the walls from burst plumbing pipes, carpets were wet with urine, and food was in short supply. Reports surfaced of elderly passengers running out of critical heart medicine and others on board squabbling over scarce food.

"I know the conditions on board were very poor," Cahill said. "I know it was very difficult, and I want to apologize again for subjecting our guests for that. ... Clearly, we failed in this particular case."

It could take up to five hours to get everybody off the huge ship.

"Inside the terminal, there's also warm food available," said Terry Thornton, Carnival's senior vice president of marketing. "There are blankets, there are cell phones and refreshments available for the guests that need that or want that assistance.

Passengers will have the options of boarding buses to Houston or Galveston, Texas, about seven hours away, or New Orleans, about two hours away, officials said.

"We have gotten our guests back to land," Cahill said. "Now, we need to get them home. ... The full resources of Carnival are working from here to get them home as quickly as we possibly can."

Stranded Carnival Cruise Ship On Its Way to Port Watch Video

Carnival Cancels All Scheduled Voyages Aboard the Triumph Watch Video

Carnival Cruise Ship Making Its Way to Port Watch Video

At an earlier news conference this afternoon, Thornton said that anyone with special needs and children will be the first to get off the boat. He said the company's No. 1 priority is to make the process as "quick, efficient and comfortable" for guests as possible.

"There are some limitations. We know that up front," Thornton said. "The ship still does not have power. We only have one functioning elevator aboard."

Click here for photos of the stranded ship at sea.

The passengers were achingly close to port about noon today as the ship began to enter the channel and proceed to the cruise terminal. At 1 p.m., the lead tow boat had a tow gear break, so a spare tug boat that was on standby had to be sent in to replace it.

But once the second tug was in position and the lines were re-set, the towing resumed only briefly before the tow line snapped.

"We had to replace that tow line, so the ship did not begin progressing back into the cruise terminal until 2 p.m.," Thornton said

Passengers desperate to get off the vessel waved at media helicopters that flew out to film the ship and passenger Rob Mowlam told ABCNews.com by phone today that most of the passengers on board were "really upbeat and positive."

Nevertheless, when he gets off Mowlam said, "I will probably flush the toilet 10 times just because I can."

Mowlam, 37, got married on board the Triumph Friday and said he and his wife, Stephanie Stevenson, 27, haven't yet thought of redoing the honeymoon other than to say, "It won't be a cruise."

Alabama State Port Authority Director Jimmy Lyons said that with powerless "dead ships" like the Triumph, it is usually safer to bring them in during daylight hours, but, "Once they make the initial effort to come into the channel, there's no turning back."

"There are issues regarding coming into the ship channel and docking at night because the ship has no power and there's safety issues there," Richard Tillman of the Mobile Bay Convention and Visitors Bureau told ABCNews.com.

When asked if the ship could be disembarked in the dark of night, Tillman said, "It is not advised. It would be very unusual."

Thornton denied the rumors that there was a fatality on the ship. He said that there was one illness early on, a dialysis patient, but that passenger was removed from the vessel and transferred to a medical facility.

The U.S. Coast Guard was assisting and there were multiple generators on board. Customs officials were to board the ship while it was being piloted to port to accelerate the embarkation, officials said.

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Water wars loom as the US runs dry

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Maldives ex-leader issues demands from Indian embassy

MALE: Former Maldivian leader Mohamed Nasheed, who has taken refuge at the Indian embassy in the capital to evade arrest, has demanded the dropping of charges against 800 party workers, his spokeswoman said Thursday.

Mariya Didi also said Nasheed wanted India to take a lead in securing an end to the political crisis in the Indian Ocean atoll nation.

Nasheed insisted that "politically motivated" charges against over 800 Maldivian Democratic Party (MDP) activists be dropped ahead of elections scheduled for September, Didi told AFP.

"We are asking all politically motivated charges including that against president Nasheed, MDP parliamentarians, MDP councillors, party officials and key party workers be dropped," she said.

In a statement issued on Wednesday night from the besieged Indian diplomatic compound, Nasheed reiterated long-standing calls for his successor Mohamed Waheed to resign and allow a caretaker government to organise the elections.

"Waheed should do the right thing and resign from office," Nasheed said.

"An interim, caretaker government should be established that can lead the Maldives to genuinely free and fair elections, in which all candidates are freely able to compete."

Nasheed sought refuge at the Indian High Commission as police tried to execute a court order seeking his arrest for failing to turn up at his trial on Sunday. Nasheed had been visiting India at the time.

The new crisis comes amid political turbulence in the up market holiday destination a year after Nasheed, the nation's first democratically elected leader, was ousted by violent protests and a mutiny by police and security forces.

"Mindful of my own security and stability in the Indian Ocean, I have taken refuge at the Indian High Commission in Maldives," Nasheed wrote on Twitter a few hours after seeking safety in the embassy building on Wednesday.

Armed police have been standing outside diplomatic compound.

Nasheed has repeatedly claimed that his trial was a politically motivated attempt to prevent him from leading his Maldivian Democratic Party into polls in September. A conviction would disqualify him.

-AFP/fl

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Instagram seeks dismissal of lawsuit over TOS change

Instagram has asked a federal court to dismiss a lawsuit over controversial terms of service changes the popular photo-sharing service announced last year.

The lawsuit, which was filed in December and seeks class-action status, accused the service of breach of contract and trying to "grab for customer property rights" after announcing revisions to its terms of service that many feared gave the service perpetual rights to sell users' photographs without payment or notification.

After a user backlash, Facebook-owned Instagram soon backpedaled on the changes and announced that the terms would revert to the version in place since the service launched in 2010.

In a filing today with the U.S. District Court for the Northern District, Instagram argues that plaintiff Lucy Funes is not entitled to her claim because she could have deleted her account before the new terms were implemented and continued to use her account on January 19, when the changes in terms of service occurred.

Instagram had said that the new terms of service would go into effect January 19 and that users could not opt out but could delete their accounts before the deadline. The lawsuit takes issue with that last point, saying customers could cancel, but that in doing so would forfeit the right to their photos.

Instagram's filing also takes issue with that point, claiming that the terms of service prior to January 19 did not claim any ownership rights to user-created content.

CNET has contacted Funes' attorney for comment and will update this report when we learn more.

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Are Honeybees Losing Their Way?

A single honeybee visits hundreds, sometimes thousands, of flowers a day in search of nectar and pollen. Then it must find its way back to the hive, navigating distances up to five miles (eight kilometers), and perform a "waggle dance" to tell the other bees where the flowers are.

A new study shows that long-term exposure to a combination of certain pesticides might impair the bee's ability to carry out its pollen mission.

"Any impairment in their ability to do this could have a strong effect on their survival," said Geraldine Wright, a neuroscientist at Newcastle University in England and co-author of a new study posted online February 7, 2013, in the Journal of Experimental Biology.

Wright's study adds to the growing body of research that shows that the honeybee's ability to thrive is being threatened. Scientists are still researching how pesticides may be contributing to colony collapse disorder (CCD), a rapid die-off seen in millions of honeybees throughout the world since 2006.

"Pesticides are very likely to be involved in CCD and also in the loss of other types of pollinators," Wright said. (See the diversity of pollinating creatures in a photo gallery from National Geographic magazine.)

Bees depend on what's called "scent memory" to find flowers teeming with nectar and pollen. Their ability to rapidly learn, remember, and communicate with each other has made them highly efficient foragers, using the waggle dance to educate others about the site of the food source.

Watch as National Geographic explains the waggle dance.

Their pollination of plants is responsible for the existence of nearly a third of the food we eat and has a similar impact on wildlife food supplies.

Previous studies have shown certain types of pesticides affect a bee's learning and memory. Wright's team wanted to investigate if the combination of different pesticides had an even greater effect on the learning and memory of honeybees.

"Honeybees learn to associate floral colors and scents with the quality of food rewards," Wright explained. "The pesticides affect the neurons involved in these behaviors. These [affected] bees are likely to have difficulty communicating with other members of the colony."

The experiment used a classic procedure with a daunting name: olfactory conditioning of the proboscis extension reflex. In layman's terms, the bee sticks out its tongue in response to odor and food rewards.

For the experiment, bees were collected from the colony entrance, placed in glass vials, and then transferred into plastic sandwich boxes. For three days the bees were fed a sucrose solution laced with sublethal doses of pesticides. The team measured short-term and long-term memory at 10-minute and 24-hour intervals respectively. (Watch of a video of a similar type of bee experiment.)

This study is the first to show that when pesticides are combined, the impact on bees is far worse than exposure to just one pesticide. "This is particularly important because one of the pesticides we used, coumaphos, is a 'medicine' used to treat Varroa mites [pests that have been implicated in CCD] in honeybee colonies throughout the world," Wright said.

The pesticide, in addition to killing the mites, might also be making honeybees more vulnerable to poisoning and effects from other pesticides.

Stephen Buchmann of the Pollinator Partnership, who was not part of Wright's study, underscored how critical pollinators are for the world. "The main threat to pollinators is habitat destruction and alteration. We're rapidly losing pollinator habitats, natural areas, and food—producing agricultural lands that are essential for our survival and well being. Along with habitat destruction, insecticides weaken pollinators and other beneficial insects."

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Dorner Not IDed, But Manhunt Considered Over

Though they have not yet identified burned remains found at the scene of Tuesday's fiery, armed standoff, San Bernardino, Calif., officials consider the manhunt over for Christopher Dorner, the fugitive ex-cop accused of going on a killing spree.

"The events that occurred yesterday in the Big Bear area brought to close an extensive manhunt," San Bernardino County Sheriff John McMahon told reporters this evening.

"I cannot absolutely, positively confirm it was him," he added.

However, he noted the physical description of the suspect authorities pursued to a cabin at the standoff scene, as well as the suspect's behavior during the chase and standoff, matched Dorner, 33.

The charred remains of the body believed to be Dorner were removed from the cabin high in the San Bernardino Mountains near Big Bear, Calif., the apparent site of Dorner's last stand. Cornered inside the mountain cabin Tuesday, the suspect shot at cops, killing one deputy and wounding another, before the building was consumed by flames.

"We did not intentionally burn down that cabin to get Mr. Dorner out," McMahon said tonight, though he noted pyrotechnic canisters known as "burners" were fired into the cabin during a tear gas assault in an effort to flush out Dorner. The canisters generate high temperatures, he added.

The deputies wounded in the firefight were airlifted to a nearby hospital, where one died, police said.

Christopher Dorner Believed Dead After Shootout with Police Watch Video

Carjacking Victim Says Christopher Dorner Was Dressed for Damage Watch Video

Christopher Dorner Manhunt: Inside the Shootout Watch Video

The deceased deputy was identified tonight as Det. Jeremiah MacKay, 35, a 15-year veteran and the father of two children -- a daughter, 7, and son, 4 months old.

"Our department is grieving from this event," McMahon said. "It is a terrible deal for all of us."

The Associated Press quoted MacKay on the Dorner dragnet Tuesday, noting that he had been on patrol since 5 a.m. Saturday.

"This one you just never know if the guy's going to pop out, or where he's going to pop out," MacKay said. "We're hoping this comes to a close without more casualties. The best thing would be for him to give up."

The wounded deputy, identified as Alex Collins, was undergoing multiple surgeries for his wounds at a hospital, McMahon said, but was expected to make a full recovery.

Before the final standoff, Dorner was apparently holed up in a snow-covered cabin in the California mountains just steps from where police had set up a command post and held press conferences during a five-day manhunt.

The manhunt for Dorner, one of the biggest in recent memory, led police to follow clues across the West and into Mexico, but it ended just miles from where Dorner's trail went cold last week.

Residents of the area were relieved today that after a week of heightened police presence and fear that Dorner was likely dead.

"I'm glad no one else can get hurt and they caught him. I'm happy they caught the bad guy," said Ashley King, a waitress in the nearby town of Angelus Oaks, Calif.

Hundreds of cops scoured the mountains near Big Bear, a resort area in Southern California, since last Thursday using bloodhounds and thermal-imaging technology mounted to helicopters, in the search for Dorner. The former police officer and Navy marksman was suspected to be the person who killed a cop and cop's daughter and issued a "manifesto" declaring he was bent on revenge and pledging to kill dozens of LAPD cops and their family members.

But it now appears that Dorner never left the area, and may have hid out in an unoccupied cabin just steps from where cops had set up a command center.

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Obama keeps faith in science and warns of cyber threats

Peter Aldhous, San Francisco bureau chief

"IT IS our unfinished task to restore the basic bargain that built this country - the idea that if you work hard and meet your responsibilities, you can get ahead."

In adopting the phrase "unfinished task" as a signature motif for his 2013 State of the Union address, President Barack Obama signalled a return to familiar themes. For those who care about investment in science, that was a reassuring message. 

The fight against global warming and the importance of technology to protect national security also got high billing. On the latter, Obama signaled that hacking skills, rather than kilotons, are increasingly a crucial currency, promising a new focus on combating cyberattacks - paralleled by negotiated cuts to the US nuclear arsenal. 

In a combative speech designed to counter Republican opponents who want to cut the budget deficit by curbing spending on Obama's priorities - including education and research - the President made the case for continued investment in innovation.

"Every dollar we invested to map the human genome returned $140 to our economy. Today, our scientists are mapping the human brain to unlock the answers to Alzheimer's; developing drugs to regenerate damaged organs; devising new material to make batteries ten times more powerful. Now is not the time to gut these job-creating investments in science and innovation. Now is the time to reach a level of research and development not seen since the height of the Space Race."

The estimate of a 140:1 return on investment in genomics comes from a 2011 study by the Battelle Memorial Institute in Columbus, Ohio. While the precise numbers from that analysis have been questioned, the importance of continued innovation to America's future economic competitiveness has been stressed in multiple reports, notably from the US National Academies. 

"Now our enemies are also seeking the ability to sabotage our power grid, our financial institutions, and our air traffic control systems. We cannot look back years from now and wonder why we did nothing in the face of real threats to our security and our economy."

Obama called on Congress to pass new legislation to counter threats from hackers backed by hostile governments. That won't be easy: last year, a bill that would have demanded that companies meet minimum standards for cybersecurity, and report if they are attacked, foundered amid complaints that it would impose large costs on US businesses. 

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Japan 'shocked' by IOC wrestling decision

TOKYO: Wrestling power Japan, which swept four gold in London, reacted with dismay Wednesday after Olympic chiefs said the 2020 Games would not include the sport, depriving the country of a rich source of medals.

"I really don't know why. I am so devastated that I don't know what to do," said Saori Yoshida, Japan's undisputed wrestling queen who has won a record 13 straight Olympic and world championship gold medals over 10 years.

Yoshida, a 55kg-class freestyle wrestler who last year received the government's "People's Honour Award" for her achievements, is the face of Tokyo's campaign for the right to host the 2020 Games.

The decision to drop wrestling, taken by the 15 members of the International Olympic Committee (IOC) executive board, has yet to be ratified by all members of the body, but leaves the sport fighting with seven other disciplines for the vacant spot in seven years' time.

Japan Wrestling Federation chairman Tomiaki Fukuda expressed his frustration at the decision.

"I am really shocked. I have no idea why they decided this," Fukuda said in an interview with TV Asahi.

He has also said on the federation's website: "I am dissatisfied and baffled. I want to know the reasons why the IOC removed wrestling."

Local media dubbed the IOC decision a "crisis for Japan's strong suit".

Chief Cabinet Secretary Yoshihide Suga also expressed disappointment at the IOC vote.

"Wrestling is one of Japan's strongest sports," he said. "It is said to be the oldest sport in the world... The decision is very disappointing."

This is the latest blow to Japanese sport after the national women's judo coach resigned in disgrace after admitting he had physically beaten his athletes as he tried to discipline them.

That scandal came just weeks after a schoolboy killed himself after repeatedly being subjected to violence by his basketball coach.

-AFP/gn

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Obama commends Apple and Intel for U.S. manufacturing

President Obama commends Apple and Intel for creating U.S. manufacturing jobs during his State of the Union address.

(Credit:
CBS News)

One of President Obama's policy points in his State of the Union speech tonight was that U.S. companies need to create jobs here. Not only did he stress this need, he also praised those companies already in the process of doing this, including Intel and Apple.

"Our first priority is making America a magnet for new jobs and manufacturing. After shedding jobs for more than 10 years, our manufacturers have added about 500,000 jobs over the past three," Obama said in his speech. "Caterpillar is bringing jobs back from Japan. Ford is bringing jobs back from Mexico. After locating plants in other countries like China, Intel is opening its most advanced plant right here at home. And this year, Apple will start making Macs in America again."

Sitting there in the audience, next to First Lady Michelle Obama, was Apple CEO Tim Cook. Cook announced in December Apple's plans to move some
Mac production to the U.S. The company is investing $100 million on this venture, Cook said.

Intel has also ramped up U.S. production over the past year by building a manufacturing plant in Arizona. The plant is expected to produce Intel's next generation of processors built on its 14-nanometer technology. The company said it was investing more than $5 billion in the facility. Giving a nod to Intel's advances with U.S. manufacturing, Obama visited the plant last January.

"It's not a bigger government we need, but a smarter government that sets priorities and invests in broad-based growth," Obama said in his State of the Union speech tonight.

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Your Shot: Blizzard Photos From Our Readers

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  Boston Seals

  Photograph by Sarah Burke, My Shot

  Last weekend’s blizzard left parts of the Northeast covered in 3 feet (0.9 meter) of snow. As people dug out, many answered our call to submit photos from the storm.

  There’s still time to submit your photos to National Geographic’s Your Shot; editors review all entries for possible publication in National Geographic magazine. Your photograph may also be included in our editors' pick of the Daily Dozen.

  Sarah Burke sent in this photo from Boston. She ventured out after the storm and captured these seals in a tank surrounded by snow.

  Published February 12, 2013

  
  











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  Sledding in the Park

  Photograph by Elena Solomon, Your Shot

  In New York City Elena Soloman snapped a bright spot in snow-blanketed Central Park: a young girl on her sled.

  Published February 12, 2013

  
  











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  Up on a Rooftop

  Photograph by Kelly Pourde, Your Shot

  The blizzard, dubbed "Nemo" by The Weather Channel, left snow piled high on the roof of Kelly Plourde’s Connecticut condo. She wrote that the wind-carved snow reminded her of "waves against the bright blue sky."

  Published February 12, 2013

  
  











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  Shaking It Off

  Photograph by Ashley Thompson, Your Shot

  Ashley Thompson’s dog, Zeppelin, shakes off snow after the blizzard visited New Jersey.

  Published February 12, 2013

  
  











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  Change of Plans

  Photograph by Scotland Willis, Your Shot

  Photographer Scotland Willis caught this snowboarder on a makeshift mogul behind a shopping center in Boston. The man’s planned ski trip had been canceled due to the storm.

  Published February 12, 2013

  
  











• 
  
  
  
  
  
  
  

  Central Park Snow

  Photograph by Casey Gomez, Your Shot

  In New York’s Central Park Casey Gomez captured a peaceful moment by the Jacqueline Kennedy Onassis Reservoir.

  Published February 12, 2013

  
  











• 
  
  
  
  
  
  
  

  Snowball Fight!

  Photograph by Dan Squire, Your Shot

  Dan Squire caught this post-storm action in Somerville, Massachusetts. "Residents celebrated the aftermath of Nemo with laughter, hot chocolate, snow sculptures, and of course," he wrote, "a huge snowball fight."

  Published February 12, 2013

  
  











• 
  
  
  
  
  
  
  

  Snow Day

  Photograph by Kelly Pourde, My Shot

  A snow pile makes the perfect slope for a bundled-up sledder. Kelly Plourde snapped this photo in Connecticut.

  Published February 12, 2013

  
  

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Great Energy Challenge Blog

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